why not check here have already been omitted; Which any discrepancies through the study as planned (and, if applicable, registered) are described.
Our study didn't see that celecoxib, the most generally prescribed selective COX two inhibitor, boosts the possibility of healthcare facility admission for coronary heart failure. Insufficient statistical electrical power is unlikely clarify such lack of proof, simply because our key analysis had eighty% electric power to detect sizeable odd ratios as little as one.08 for the current utilization of celecoxib.
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We described the day of the 1st admission for heart failure recognized in the course of adhere to-up as being the index date. Codes utilized to identify heart failure cases in Every database are claimed during the supplementary materials (table S1).
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Were being admitted to hospital with a Key analysis of coronary heart failure while in the year before the date of cohort entry, to stay away from the inclusion of occasions happening ahead of the commence of NSAIDs use (Observe that secondary clinic or outpatient coronary heart failure diagnoses were not regarded as exclusion criteria).